I don’t necessarily think that the “toe thumb” phenonema is weird and discomforting. However if you have an actual toe as your thumb, I might be a little weirded out. Especially if it appears to be as large as the jokethumb Pee-Wee Herman used to hitchhike. Below is a video and a link to the story.
(MURDOCK EDIT: Does this mean we can sew human thumbs on apes and they can take over the world? Please? Maybe we could start by sewing them onto their foreheads. That’d be weird. But I’d laugh.)